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AOCS Phospholipid Division
Newsletter October 2007

Synthesis of 1,3- and 1,2-Diphosphatidylglycerol

Moghis U. Ahmad, U. Murali Krishna, Shoukath M. Ali, Sreeti Choudhury, Imran Ahmad. Lipids (2007) 42:291-296

Abstract A novel phosphonium salt methodology was utilized for the first time to synthesize 1,3- and 1,2-diphosphatidylglycerol. Optically active 1,2-di-O-acyl-sn-glyceryl phosphate was coupled with unprotected glycerol in the presence of pyridiniumbromide perbromide and triethylamine to yield, after final removal of the phosphate protecting group, the title compounds. The 1,2-diphosphatidylglycerol (1,2-isomer of cardilipin) may be a member of a new class of phospholipids for industrial applications similar to other phosphocholines.

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Also in this newsletter:

Message from the Chair, Jonathan Maynes

31P-NMR Round Robin Tests on Phospholipids, by Bernd W. K. Diehl, Ph.D.

Ring trial validation of a method for the extraction of DNA from soy lecithins, by Waiblinger, H. U.; Ernst, B.; Graf, N.; Pietsch, K.

In Memoriam: David W. Yesair (from inform August 2007)

Results of AOCS Lecithin Short Course Québec 2007, by Willem van Nieuwenhuyzen

Technical Program 2007

Patent Applications: Enzymatic modification of lecithin

Extracts and Distillates: Phospholipid species analysis

Business News: Tight oilseed/oil markets forecast

AOCS, 2710 S. Boulder, Urbana, IL 61802-6996 USA

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Member-at-Large
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